Research topic: neurosteroids
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چکیده
منابع مشابه
Research topic: neurosteroids
Thirty years ago, the group of Baulieu and colleagues discovered that certain steroid hormones were present in higher amounts in the brain than in the plasma, and also found that suppression of circulating steroids by adrenalectomy and castration does not affect the concentration of pregnenolone, dehydroepiandrosterone, and their sulfate esters in the rat brain. These seminal observations led t...
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Neurosteroids are a group of steroid hormones synthesized by the brain in the presence of steroidogenic enzymes. Specific neurosteroids modulate function of several receptors, and also regulate growth of neurons, myelinization and synaptogenesis in the central nervous system. Some neurosteroids have been shown to display neuroprotective properties, which may have important implications for thei...
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ژورنال
عنوان ژورنال: Frontiers in Endocrinology
سال: 2012
ISSN: 1664-2392
DOI: 10.3389/fendo.2012.00126